Our lab in the Division of Cancer Genetics and Epigenetics at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center Department of Oncology is seeking applicants for a Research Technologist position. The position is available in the labs of Dr. Steve Baylin and Hari Easwaran (NIH-funded laboratory at the Johns Hopkins University School of Medicine). The lab studies epigenetics mechanisms in cancer development, role of age-associated epigenetic changes in cancer development with the goal of translating research from bench to bedside. The candidate is expected to work towards development of single cell epigenetic assays for DNA methylation mapping for understanding epigenetic alterations during early tumorigenesis. The research has implications in basic cancer research and cancer diagnostics. Within this role, this individual will employ cell lines, organoid culture and mouse models to study mechanisms underlying epigenetic alterations in cancers as they relate to tumorigenesis, as well as therapeutic and diagnostic applications.
The Research Technologist will work under the supervision of a Faculty Investigator or Postdoctoral Fellow and will be responsible for laboratory maintenance and molecular biology experiments to support the ongoing projects in the lab. The research will study mechanisms underlying epigenetic alterations in cancers as they relate to tumorigenesis, as well as therapeutic and diagnostic applications. A principal component of the project goals are to develop singe cell epigenetic assays requiring skills in DNA manipulating enzymes as well as handling cell culture.
The ideal candidate will be a self-motivated individual with excellent work ethic and organizational skills. A Bachelor's Degree in Biology, Biochemistry, Chemistry or a related field is required and prior experience in biomedical laboratory research is preferred. This position is fully funded.
Specific Duties & Responsibilities:
Maintaining laboratory equipment, stocks, and supplies
Tracking and accessioning orders
Managing supply and reagent stocks
Preparing laboratory solutions and reagents
Following established procedures and protocols to support lab projects
Implementing basic understanding of theory behind experiments to carry out protocols and identify and trouble-shoot obstacles
Recording data resulting from molecular biology experiments
Analyzing data from molecular biology experiments
Communicating with lab members to coordinate work, share progress, and identify areas in need of troubleshooting
Minimum Qualifications (Mandatory):
Bachelor's Degree in Biology, Biochemistry, Chemistry or a related field
Experience in molecular biology techniques (e.g., DNA preparation, PCR, DNA manipulation using enzymes, cloning, other common DNA/RNA/protein techniques) and mammalian tissue culture desired.
Exceptional organizational and communication skills
Self-motivation and an interest in biomedical careers
Microsoft office proficiency, especially Excel
* Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.
Masters Degree (Biotechnology, Biomedical Engineering or other related life sciences fields)
Prior biomedical laboratory research experience
Previous background in cancer research and epigenetics will be an advantage
Special Knowledge, Skills & Abilities:
Ability to work both independently as well as part of a team
Enthusiasm, reliability, and dedication
Ability to learn new computer skills and applications quickly
Eligible to work in USA
Classified Title: Research Technologist Role/Level/Range: ACRO40/E/02/CC Starting Salary Range: $15.00 - $20.00/hr (commensurate with experience) Employee group: Full Time Schedule: M-F 8:30am-5pm Exempt Status: Non-Exempt Location: School of Medicine Campus Department name: SOM Onc Cancer Biology Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
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