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Research Specialist II
The Dalton Laboratory is seeking a highly motivated Research Specialist II  to conduct research into the biologic and therapeutic implications of spliceosome mutations in myeloid malignancies (acute myeloid leukemia and myelodysplastic syndromes). The laboratory uses gene editing to engineer and then study unique human cell models of cancer-associated mutations in spliceosome genes and validates findings in primary human patient samples. Biological studies include analysis of mutation-induced RNA splicing, proteome changes, and diverse cellular pathway alterations including those in energy metabolism. Therapeutic studies include targeting metabolic weaknesses, characterizing therapeutic a


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