The Department of Anesthesiology and Critical Care Medicine at Johns Hopkins University School of Medicine is seeking a Research Technologist. We are looking for qualified candidates with interest and experience in working with animal models, to join a multidisciplinary group working in the cutting-edge area of exploring pathogenesis, pharmacokinetics, and noninvasive imaging (in vivo PET/CT) a pediatric rabbit model of central nervous system Tuberculosis. The position comes with opportunities to learn and partake in cutting-edge infectious diseases research (metabolomics, single cell-RNA-sequencing, etc.) and cultivate mentorships with physician-scientists in translational research.
This work is part of funded projects (NIH) to optimize tuberculous meningitis treatment using mass spectrometry, novel positron emission tomography (PET) radiotracers, antimicrobial treatment and host-directed therapy in the rabbit model. The candidate should have an interest in immunology/neuroscience, infectious disease pathogenesis (Tuberculosis), pharmacokinetics or related fields.
Specific Duties & Responsibilities
Use basic science knowledge to learn techniques/methods of the lab.
Conduct and score neurobehavior tests in rabbits.
Perform laboratory experiments with animal models (rabbits) which includes necropsies and tissue processing (sectioning) for immunohistochemistry, microscopy, biochemistry, molecular biology, and cell culture.
Identify and resolves common problems involved in routine research assays.
Recommend revisions to experimental methods based upon observations of the data and troubleshooting.
Train users in standard equipment operation and routine lab techniques and procedures.
Prepare, test, and maintain standard laboratory equipment.
Collect project data, organize/collate, and analyze data.
Increase own skill base and knowledge of lab research and relevant assays.
Assist in the cultivation of Mycobacterium tuberculosis.
Work with animal care/veterinary staff and monitor the health of animals during experiments, with an emphasis on adhering to IACUC guidelines.
Follow bio-hazardous material protocols under Biosafety Level 2 and Biosafety Level 3 conditions.
Perform related laboratory maintenance, participate in cleaning rotation of common laboratory space/equipment and monitor inventory of supplies.
Monitor inventory levels, order materials and supplies in accordance with established policies and procedures and monitor order upon receipt.
Gain problem-solving skills through progressive training, understanding of the research and experience.
Understand the role of senior lab members and accept constructive guidance.
Interact with faculty, lab, animal facilities and administrative staff, students, postdoctoral fellows, and outside vendors.
Demonstrate organization, curiosity, problem solving, resourcefulness, and flexibility.
*This description is a general statement of required duties and responsibilities performed on a regular and continuous basis. It does not exclude other duties as assigned.
Bachelor's Degree in Biology, Chemistry, or a related field.
Some related post-undergraduate work experience preferred.
Research experience in any of these areas are highly desired but not required.
processing and handling of brain tissue.
tissue sectioning and immunohistochemistry.
basic microscopy or confocal imaging.
animal handling and behavior evaluation.
bacterial handling and culture.
pharmacokinetic basics, or proficiency with statistical software.
Classified Title: Research Technologist Role/Level/Range: ACRO40/E/02/CC Starting Salary Range: $15.00-$20.40 HRLY (Commensurate with experience) Employee group: Full Time Schedule: Monday-Friday with occasional weekends/evening hours Exempt Status: Non-Exempt Location: School of Medicine Campus Department name: SOM Ane Research Personnel area: School of Medicine
Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines:
*JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
**Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.
The successful candidate(s) for this position will be subject to a pre-employment background check.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
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The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
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