We are seeking a highly motivated, energetic Research Technologist with an interest in biomedical research to work in the field of Retinal Regenerative Medicine. We use stem cell biology to study human neuronal and glial cells. We use CRISPR genome editing to develop models of: 1) human retinal disease, with a focus on neurodegenerative diseases such as glaucoma, and 2) demyelinating diseases (such as multiple sclerosis where myelin sheath on the CNS neurons is lost).
Specific Duties & Responsibilities
This work will involve considerable amounts of cell culture work.
Working under the supervision of the principal investigator and other laboratory personnel, the successful applicant will be responsible for maintaining human pluripotent stem cells, and differentiating them into human retinal ganglion and human oligodendrocyte cells.
He/she will also assist in various drug discovery work to identify small molecules, genes, and pathways relevant to oligodendrocyte development, with the ultimate goal of developing novel therapeutic strategies for patients with multiple sclerosis and other demyelinating disorders.
Bachelor's Degree in Biology, Chemistry, or related field is required.
Familiarity with basic laboratory techniques, including DNA and RNA extraction, PCR, qPCR, Western Blotting, and cell culture is desirable
Experience with cell culture work, ideally with human stem cell culture, is required.
Ability to maintain clear written records and be able to carry-out experiments with minimal supervision.
Good communication skill and ability to read and interpret scientific articles and scientific data.
Careful attention to detail and thoughtfulness on how to interpret, troubleshoot and improve experiments.
Some relevant post-undergraduate work experience in the field of cellular and molecular biology is desirable.
Classified Title: Research Technologist Role/Level/Range: ACRO40/E/02/CC Starting Salary Range: $15.00-$20.40 HRLY (Commensurate with experience) Employee group: Full Time Schedule: Mon - Fri; 8:30 - 5:00 with some weekends Exempt Status: Non-Exempt Location: School of Medicine Campus Department name: SOM Oph Ocular Molecular Biology Personnel area: School of Medicine
Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines:
*JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
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