Senior Research Technician - Center for Patient Derived Models
Dana-Farber Cancer Institute
Location: Boston, Massachusetts
Internal Number: 2023-32250
The Center for Patient Derived Models (CPDM) at DFCI is seeking applicants for the position of Senior Research Technician. This is an innovative Center at the DFCI which seeks to advance modeling science by performing research on patient-derived xenografts, organoids, cell lines, and personalized drug screening of fresh patient cells using innovative and high content approaches. Applicants are desired to have prior experience in laboratory and animal research methods. The applicant will work to advance our knowledge of precision medicine, cancer biology, treatment and diagnostics in all adult and pediatric cancer types. Applicants hired to this position will apply modern cutting-edge techniques to create and study patient derived models of cancer (patient derived cell lines, patient derived xenografts, and cancer immunotherapy models, and Avatars).
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Center for Patient Derived Models (CPDM) - Dana-Farber Cancer Institute | Boston, MA
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The position will involve use of in-vitro and in-vivo methods to develop and study patient cancer models that can aid in novel targeted therapy development and diagnosis of treatment effects. Applicants will participate in preclinical studies in PDX mouse trials, high throughput screening, high-content screening, stem cell methods, and preclinical and clinical trials execution and support. Applicants with prior experience in animal research and procedures (mouse/PDX), cell culture (2D, 3D and primary cell culture), preclinical, human research, pathology, and drug screening techniques are preferred.
Developing independence will be fostered, and opportunities for intellectual input and contribution to manuscripts will also be readily available. The position will have opportunity to interact with a wide range of clinicians and scientific collaborators. The position will be supervised by the Center Director (Dr. Keith Ligon) and Co-Director.
Design and execute experiments for different projects in-line with the center???s mission and goals
This position is responsible for performing various preclinical animal research methods in conventional, immunodeficient and transgenic/knockout rodent colonies.
May be responsible for the examination of animals and specimens to detect the presence of disease or other problems.
Conduct standardized biological, molecular or biochemical tests and laboratory analyses, including the collection of information and samples from organic substances, such as tissue, blood, drugs, and animals.
Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. May be expected to participate in formal and information presentations of results to staff.
May be responsible for the development, modification and improvement of standard operating procedures.
Participate in grant application process and manuscript preparation as required.
Maintains detailed notebook and databases of all work-related activities.
Monitors laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.
Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors.
Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.
May be responsible for monitoring laboratory budgets.
Bachelors of Science with?? 2+ years experience or Masters with lab experience required. Experience in cancer cell & molecular biology, neuroscience, bioengineering, biochemistry, or related scientific field is preferred. Excellent organization and data management skills are required. We are looking for candidates who have at least two years of availability. Position is available immediately.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.?? As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.?? Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to under-served members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.