Dr. Jeff Mumms laboratory (Wilmer Eye Institute, Johns Hopkins University), is seeking a CO Research Technologist. The goal of the research is to understand how neural circuits are formed, how they function, and how they can be regenerated. We utilize zebrafish for our studies due to significant advantages afforded by this model system. The most important advantage being that zebrafish have a robust regenerative capacity that extends even to the nervous system. We also use cell-type specific labelling methods and confocal microscopy to make movies of how cells develop and/or behave directly in living animals. In addition, the lab is conducting a chemical drug screen to identify small molecule compounds that enhance the ability of zebrafish to regenerate lost tissues. This multi-prong approach facilitates investigations that allow us to visualize how neural circuits are established and identify genetic factors that regulate regenerate. In addition, the chemical drug screen will serve to reveal possible therapeutic targets in various human degenerative diseases.
Specific Duties & Responsibilities
The position will require a thorough understanding and vigilant implementation of standard scientific methods.
The Research Technologistwill be expected to gain an understanding of the theory behind experiments and apply critical analytical skills during assigned projects in order to identify key findings and trouble-shoot problems.
Attention to detail is extremely important.
Conduct routine assays analyzing small chemical compounds and/or genetic mutations for their ability to effect regeneration.
Help maintain and monitor a large Zebrafish facility.
Help maintain and monitor various shared index databases.
Transgenic plasmid preparation and microinjection.
Assist other research personnel in the lab as needed.
Bachelor's Degree in Biology, Chemistry or related field.
Some related post-undergraduate work experience preferred.
Previous research related work experience is preferred, in particular with the following techniques/experiences,
Zebrafish husbandry (e.g. general care, breeding, genotyping, phenotyping, drug treatments)
High resolution imaging (fluorescence and confocal microscopy)
Histological and immunological tissue processing.
Standard Molecular Biology techniques.
Must be able to work both independently and in a collaborative manner with a diverse group of researchers.
Classified Title: Research Technologist Working Title: CO Research Technologist Role/Level/Range: ACRO40/E/02/CC Starting Salary Range: $15.00-$20.40-$25.50 HRLY (Commensurate with experience) Employee group: Full Time Schedule: Mon-Fri 8:00 – 5:00 Exempt Status: Non-Exempt Location: Hybrid/School of Medicine Campus Department name: SOM Oph Ocular Genetics Research Center Personnel area: School of Medicine
Total Rewards The referenced salary range is based on Johns Hopkins University's good faith belief at the time of posting. Actual compensation may vary based on factors such as geographic location, work experience, market conditions, education/training and skill level. Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/
Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines:
JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
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